{"id":122995,"date":"2024-05-12T19:30:58","date_gmt":"2024-05-12T16:30:58","guid":{"rendered":"https:\/\/milliycha.uz\/?p=122995"},"modified":"2024-05-12T19:31:04","modified_gmt":"2024-05-12T16:31:04","slug":"kimyoterapiya","status":"publish","type":"post","link":"https:\/\/milliycha.uz\/kr\/kimyoterapiya\/","title":{"rendered":"Kimyoterapiya"},"content":{"rendered":"\n

Kimyoterapiya, kimyoviy usul b-n davolash \u2014 xavfli o’smalarga qarshi ta’- sir etish xususiyatiga ega dori vositala- ri b-n davolash. Bu usul bundan 50 yil avval olimlar tomonidan kashf etilgan; unda azotipritning ba’zi farmakolo- gik moddalari tez o’suvchi hujayralarga ta’sir etishi va qon i.ch. a’zolarining xavfli o’smasida qo’llash mumkinli- gi bayon etilgan. Keyinchalik shu asosda K.da qo’llaniladigan dorilar ishlab chiqarila boshlandi. K.da qo’llaniladigan dori vosita- lari farmakologik xususiyatiga ko’ra, jadal o’sayotgan hujayralarning ri- vojlanishi va ko’payishini jilovlash va izdan chiqarish, shuningdek, DNK, RNK yoki tegishli oqsillar sintezini to’xtatish, ya’ni tsitostatik ta’sirga ega. 50 dan ortiq bunday tabiiy va sun’iy (sintetik) preparatlar: alkillovchi- lar (embixin, xlorbutin, tsiklofosfan, ifosfamid, prospidin, sarkolizin va h.k.), antimetabolitlar (metotreksat, ftorurasil, ftorafur, kapesitabin- kseloda, gemzar va b.), xavfli o’smaga qarshi qo’llaniladigan antibiotiklar (daktinomisin, rubomisin, doksorubi- Tsin, Adriamisin, bleomisin va b.), do- rivor o’simliklardan ajratib olingan vinblastin, vinkristin, navelbin, taksol, taksoter, Topotekan, irinotekan, Etopozid va b. dorilar hamda gormonlar ishlatiladi. Qon yaratish a’zolari va limfa tu- gunlari xavfli o’smasi (gemoblastoz, limfoma) rak (saraton) kasalligining tarqalgan xillarida K. asosiy davolash usuli hisoblanadi. Saraton kasalligi- ning O’chokli (tarqalmagan) holatlarida keyingi yillarda yangi ta’sirchan Pre- paratlar (taksol, navelbin, gemzar, tsisplatin) ishlab chiqarilishi tufayli K. ni kompleks davolash tarkibiga ki- ritish mumkin, mas, xirurgik usuldan oldin (neoad’yuvant) yoki undan keyin kasallik tarqalishining oldini olish maqsadida profilaktik (ad’yuvint) K. qo’llaniladi. Ayrim xavfli o’sma kasalliklarida (bachadon xoriokarsinomasi, bolalarda uchraydigan limfoblasteloykoz, limfo- granulematoz) K. yaxshi naf berishi va bemor sog’ayib ketishi mumkin. Ayrim xavfli o’smalar (buyrak, me’- da osti bezi raki) kimyoviy dorilarga nisbatan kam sezgirligi sababli K.da qo’llaniladigan dorining davoli xusu- siyati tegishli baholash darajadari b-n belgilanadi. Ba’zan K.dan so’ng ayrim noxush aso- ratlar kuzatiladi, lekin keyinchalik bu holat o’z-o’zidan yo’qolib ketishi mumkin.<\/p>\n","protected":false},"excerpt":{"rendered":"

Kimyoterapiya, kimyoviy usul b-n davolash \u2014 xavfli o’smalarga qarshi ta’- sir etish xususiyatiga ega dori vositala- ri b-n davolash. Bu usul bundan 50 yil avval olimlar tomonidan kashf etilgan; unda … Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":99837,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[201],"tags":[],"class_list":["post-122995","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-k-harfi","entry"],"translation":{"provider":"WPGlobus","version":"3.0.2","language":"kr","enabled_languages":["uz","kr","ru"],"languages":{"uz":{"title":true,"content":true,"excerpt":false},"kr":{"title":false,"content":false,"excerpt":false},"ru":{"title":false,"content":false,"excerpt":false}}},"_links":{"self":[{"href":"https:\/\/milliycha.uz\/kr\/wp-json\/wp\/v2\/posts\/122995","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/milliycha.uz\/kr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/milliycha.uz\/kr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/milliycha.uz\/kr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/milliycha.uz\/kr\/wp-json\/wp\/v2\/comments?post=122995"}],"version-history":[{"count":1,"href":"https:\/\/milliycha.uz\/kr\/wp-json\/wp\/v2\/posts\/122995\/revisions"}],"predecessor-version":[{"id":123011,"href":"https:\/\/milliycha.uz\/kr\/wp-json\/wp\/v2\/posts\/122995\/revisions\/123011"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/milliycha.uz\/kr\/wp-json\/wp\/v2\/media\/99837"}],"wp:attachment":[{"href":"https:\/\/milliycha.uz\/kr\/wp-json\/wp\/v2\/media?parent=122995"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/milliycha.uz\/kr\/wp-json\/wp\/v2\/categories?post=122995"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/milliycha.uz\/kr\/wp-json\/wp\/v2\/tags?post=122995"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}